Here are the Carnegie Mellon University Tartans all-time assists leaders.
| Name | Years | Amt |
| Colin McNeil | 2016-20 | 458 |
| Todd Jenkins | 1989-93 | 442 |
| Corey O’Rourke | 2005-09 | 364 |
| Dan Donohoe | 1978-82 | 331 |
| Eliot Goren | 2001-05 | 322 |
| Tom Franklin | 1984-88 | 288 |
| Mike Hosni | 1990-94 | 279 |
| Mariano DeFilippo | 1976-80 | 276 |
| George Harvey | 1976-78 | 264 |
| Greg Gabriel | 1981-84 | 261 |