Here are the Iowa State Cyclones all-time blocks leaders.
- 235 Jared Homan, 2002-05
- 189 Kelvin Cato, 1996-97
- 134 Loren Meyer, 1992-95
- 128 George Conditt IV, 2019-22
- 120 Victor Alexander, 1988-91
- 115 Sam Hill, 1984-87
- 114 Jameel McKay, 2015-16
- 109 Rahshon Clark, 2005-08
- 99 Craig Brackins, 2008-10
- 92 Cameron Lard, 2018-19
- 89 Marcus Fizer, 1998-2000
- 87 Solomon Young, 2017-21
- 82 Julius Michalik, 1992-95
- 78 Jamie Vanderbeken, 2009-11
- 71 Ron Falenschek, 1980-83
- 70 Jackson Vroman, 2003-04
- 67 Georges Niang, 2013-16
- 65 Deonte Burton, 2016-17
- 62 Elmer Robinson, 1986-89
- 61 Jeff Grayer, 1985-88