Here are the SIUE Cougars all-time assists leaders.
| Assists | Years | ||
| 1. | 565 | J.B. Jones | 2004-08 |
| 2. | 437 | Keil Peebles | 1975-79 |
| 3. | 370 | Brian Karvinen | 1991-94 |
| 4. | 316 | Shaun Smoot | 1995-98 |
| 5. | 299 | Kenny Stanley | 1984-87 |
| 6. | 293 | Frankie Williams | 1985-89 |
| 7. | 277 | Kris Davis | 2011-15 |
| 8. | 261 | Tony Johnson | 1971-73 |
| 9. | 257 | Tim Bauersachs | 2001-05 |
| 257 | Christian Ellis | 2016-19 | |
| 11. | 253 | Donivine Stewart | 2013-15 |
| 12 | 242 | Tyresse Williford | 2018-20 |
| 13. | 232 | Aamir McCleary | 2008-10 |
| 14. | 222 | Scott Kabbes | 1979-81 |
| 15. | 211 | Don Koppenhaver | 1973-75 |
| 16. | 210 | Courtney Carter | 2020-22 |
| 17. | 198 | Anthony Jones | 2004-08 |
| 18. | 194 | Greg Payne | 1975-77,78-80 |
| 19. | 192 | Ted Smith | 1979-81 |
| 192 | Kevin Caldwell | 1990-92 | |
