Here are TMU Mustangs single season blocks leaders.
| 90 Tim Soares 2017-18 |
| 69 Tim Soares 2018-19 |
| 65 Paul Brown 2011-12 |
| 62 Tim Soares 2019-20 |
| 60 Raphael Harris 2009-10 |
| 56 Paul Brown 2010-11 |
| 55 Joe Jon Bryant 1991-92 |
| 54 Raphael Harris 2007-08 |
| 52 Jacy Armbruster 1999-2000 |
| 51 Tim Soares 2016-17 |
| 43 Brian Wilson 1997-98 |
| 43 Paul Brown 2012-13 |